Three cases of pruritic urticarial papules and plaques of pregnancy (PUPPP) treated with intramuscular injection of autologous whole blood.

نویسندگان

  • I K Jeon
  • H R On
  • S H Oh
  • S K Hann
چکیده

BACKGROUND Pruritic urticarial papules and plaques of pregnancy (PUPPP), also known as polymorphic eruption of pregnancy, is a common and benign but exceedingly uncomfortable dermatosis of pregnancy. Investigation of new treatment options has been limited by patient concerns about the negative fetal effects of medication. OBJECTIVE To assess the efficacy of intramuscular injection of autologous whole blood (AWB) for treatment of PUPPP. METHODS This is a retrospective descriptive case series of three patients with PUPPP, all of whom were treated with intramuscular injection of AWB. RESULTS All patients showed good responses to intramuscular injection of AWB, tolerated the treatment, and there were no adverse effects to the patients or their babies. CONCLUSION AWB may be an alternative treatment option for patients with PUPPP who are worried about the risk of medication use during pregnancy or breastfeeding. Whole blood collected from the patient's own body may be preferable to foreign medications. Future investigation into the exact mechanism with controlled clinical studies using a large number of patients will be necessary to provide supporting evidence for this potential treatment.

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منابع مشابه

Pruritic Urticarial Papules and Plaques of Pregnancy Occurring Postpartum Treated with Intramuscular Injection of Autologous Whole Blood

Pruritic urticarial papules and plaques of pregnancy (PUPPP)(also known as polymorphic eruption of pregnancy in Europe) is an intensely pruritic eruption that affects women during the third trimester of pregnancy. Treatment usually is aimed at symptom relief until delivery, as the eruption usually resolves rapidly in the postpartum period. We report the case of a 30-year-old woman who presented...

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Pruritic urticarial papules and plaques of pregnancy (PUPPP).

Pruritic urticarial papules and plaques of pregnancy (PUPPP) is a rare dermatosis of unknown etiology that is most frequently seen in primiparas and twin/multiple pregnancies. The prognosis is favorable. We report a case of PUPPP in a primipara and review the clinical signs, differential diagnosis, possible etiologic factors, diagnosis, and therapy.

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Pruritic urticarial papules and plaques of pregnancy.

Pruritic urticarial papules and plaques of pregnancy (PUPPP) are among the most common pruritic dermatoses observed in pregnant women. PUPPP appears most frequently in the third trimester, in primigravidas, and in multiple gestation pregnancies. The eruption of changes occurs initially on the abdomen and extends over the thighs, legs, back, buttocks, arms, and breasts. Skin changes typical for ...

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Pruritic Urticarial Papules and Plaques of Pregnancy Developing in a Gravida having Overt Diabetes with Hypothyroidism, Pre-eclampsia and Anemia

Specific dermatoses of pregnancy refer to a group of skin diseases that are encountered predominantly during or immediately following pregnancy. This is a case report of pruritic urticarial papules and plaques of pregnancy developing in a 29-year-old lady primigravida lady is associated with overt diabetes with hypothyroidism, pre-eclampsia and anemia. The diagnosis of PUPPP is a clinical one, ...

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عنوان ژورنال:
  • Journal of the European Academy of Dermatology and Venereology : JEADV

دوره 29 4  شماره 

صفحات  -

تاریخ انتشار 2015